Spectrum of the neurologic manifestations in childhood-onset cryopyrin-associated periodic syndrome


Kilic H., ŞAHİN S., Duman C., Adrovic A., BARUT K., Turanli E. , ...More

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, vol.23, no.3, pp.466-472, 2019 (Journal Indexed in SCI) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1016/j.ejpn.2019.03.006
  • Title of Journal : EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
  • Page Numbers: pp.466-472
  • Keywords: Cryopyrin-associated periodic syndrome, Anti interleukin-1, Children, Autoinflammatory syndrome, COLD AUTOINFLAMMATORY SYNDROME, NLRP3 GENE, MUTATION, CANAKINUMAB, MANAGEMENT

Abstract

Objective: Neurologic complications of chronic infantile neurologic, cutaneous and articular syndrome (CINCA) are well-known, whereas there are scarce data regarding neurologic features of milder cryopyrin-associated periodic syndrome (CAPS) phenotypes. We aimed to review the neurologic features in detail and summarize the other CAPS-related manifestations in 12 children.