Attention Deficit Hyperactivity Disorder Comorbidity in an Adolescent Diagnosed with L-2 Hydroxyglutaric Aciduria and Response to Atomoxetine Treatment: a Case Report


Yektas C., Tufan A. E.

DUSUNEN ADAM-JOURNAL OF PSYCHIATRY AND NEUROLOGICAL SCIENCES, cilt.29, ss.271-274, 2016 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 29 Konu: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5350/dajpn2016290309
  • Dergi Adı: DUSUNEN ADAM-JOURNAL OF PSYCHIATRY AND NEUROLOGICAL SCIENCES
  • Sayfa Sayısı: ss.271-274

Özet

L-2-hydroxyglutaric aciduria (L-2 HGA) is a rare, neurodegenerative, slowly progressing and autosomal recessively inherited metabolic disorder. The disease progresses with mental retardation, behavioral disorder, ataxia, extrapyramidal signs and epileptic seizures. Diagnosis is made by detection of increased levels of L-2-hydroxyglutaric acid in urine, plasma or cerebrospinal fluid. In this report, we presented a 13 year old male patient diagnosed with L-2 HGA and had seizures, intellectual disability, attention deficit hyperactivity disorder (ADHD) symptoms and failure in school performance. Here we discussed this rare disease with ADHD symptoms and the response to atomoxetine treatment.