MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours

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Bulkowska M., Rybicka A., Senses K. M., Ulewicz K., Witt K., Szymanska J., ...Daha Fazla

BMC CANCER, cilt.17, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1186/s12885-017-3751-1
  • Dergi Adı: BMC CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: microRNA, Canine mammary cancer, Human breast cancer, HUMAN BREAST-CANCER, GENE-EXPRESSION, CELL-CYCLE, PROGRESSION, BIOMARKERS, APOPTOSIS, PLASMA, GROWTH, SERUM, DOGS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: MicroRNAs may act as oncogenes or tumour suppressor genes, which make these small molecules potential diagnostic/prognostic factors and targets for anticancer therapies. Several common oncogenic microRNAs have been found for canine mammary cancer and human breast cancer. On account of this, large-scale profiling of microRNA expression in canine mammary cancer seems to be important for both dogs and humans.