Quercetin Improves Inflammation, Oxidative Stress, and Impaired Wound Healing in Atopic Dermatitis Model of Human Keratinocytes
PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY, vol.33, no.2, pp.69-79, 2020 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 33 Issue: 2
- Publication Date: 2020
- Doi Number: 10.1089/ped.2019.1137
- Journal Name: PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database
- Page Numbers: pp.69-79
- Keywords: atopic dermatitis, inflammation, quercetin, keratinocyte, wound healing, THYMIC STROMAL LYMPHOPOIETIN, STEM-CELL SURVIVAL, EPITHELIAL-CELLS, TNF-ALPHA, IN-VITRO, SKIN, MIGRATION, EXPRESSION, CYTOKINES, ACTIVATION
- Acibadem Mehmet Ali Aydinlar University Affiliated: No
Abstract
Background: Atopic dermatitis (AD) is a common inflammatory skin disease with complex pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties in many human diseases. In this study, the potential bioactive effect of quercetin, a polyphenolic plant-derived flavonoid, on the AD model of human keratinocytes was evaluated.