Opioids and analgesics use after adult spinal deformity surgery correlates with sagittal alignment and preoperative analgesic pattern

Bourghli A., Boissiere L., Larrieu D., Kaissar F., Cawley D., Fujishiro T., ...More

EUROPEAN SPINE JOURNAL, vol.29, no.1, pp.73-84, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1007/s00586-019-06141-8
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.73-84
  • Keywords: Opioids, NSAID, Adult spinal deformity, Health-related quality of life scores, Sagittal alignment, QUALITY-OF-LIFE, NONOPERATIVE TREATMENT, RADIOGRAPHIC PARAMETERS, LEG PAIN, SCOLIOSIS, IMPACT, ASSOCIATION, MANAGEMENT, OUTCOMES
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


PurposeTo assess pain, health-related quality of life (HRQOL) scores and sagittal parameters of adult spinal deformity (ASD)-operated patients in the context of their analgesic consumption especially opioids (narcotics) over the first year postoperative period.MethodsIn total, 372 patients from a multicenter database were stratified into 3 groups at baseline: 241 patients in the minimal group (no analgesic, or NSAIDs/narcotics weekly or less), 64 in the NSAIDs every day group and 67 in the narcotics every day group. HRQOL and back and leg pain scores were evaluated at 6 months and 1 year postoperatively. Also several sagittal alignment parameters were assessed.ResultsSignificant improvements in pain and HRQOL scores were observed across all 3 groups by 1 year (P<0.05) postoperatively. While the minimal group had the best pre- and postoperative HRQOL scores, the NSAID group demonstrated the best improvement in HRQOL. Only the minimal group displayed continued improvement from 6 months to 1 year. 90%, 65% and 40% of minimal, NSAID and narcotic groups of patients, respectively, no longer took any analgesics at 1 year postoperatively. Alternatively, 36% of patients in the narcotics group continued to take narcotics at 1 year. Residual malalignment increased NSAIDs consumption in different groups at 1 year.ConclusionThis study evaluated the analgesics use after ASD surgery in relation to the clinical and radiological outcomes. Despite important postoperative opioids consumption in the narcotics group, clinical outcome yet improved. Malalignment parameters demonstrated a predictive value in regard to NSAIDs' usage.