Sample collections from healthy volunteers for biological variation estimates' update: a new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine


Carobene A., Strollo M., Jonker N., Barla G., Bartlett W. A. , Sandberg S., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.54, no.10, pp.1599-1608, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 10
  • Publication Date: 2016
  • Doi Number: 10.1515/cclm-2016-0035
  • Title of Journal : CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Page Numbers: pp.1599-1608
  • Keywords: biobank, biological variation, preanalytical phase, GAMMA-GLUTAMYL-TRANSFERASE, REFERENCE CHANGE VALUES, C-REACTIVE PROTEIN, ASPARTATE-AMINOTRANSFERASE, ALANINE AMINOTRANSFERASE, QUALITY SPECIFICATIONS, VARIABILITY, HEMOGLOBIN, INTERVALS, ANALYTES

Abstract

Background: Biological variation (BV) data have many fundamental applications in laboratory medicine. At the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) the reliability and limitations of current BV data were discussed. The EFLM Working Group on Biological Variation is working to increase the quality of BV data by developing a European project to establish a biobank of samples from healthy subjects to be used to produce high quality BV data.