Evaluation of the Effects of a High Dose of Erythropoietin-beta on Early Endotoxemia Using a Rat Model

Eren Z., Coban J., Ekinci I. D. , Kaspar C., Kantarci G.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.21, no.3, pp.321-329, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2012
  • Title of Journal : ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Page Numbers: pp.321-329
  • Keywords: erythropoietin, lipopolysaccharide, endotoxemia, acute kidney injury, ACUTE-RENAL-FAILURE, TISSUE PROTECTION, INJURY

Abstract

Background. Endotoxins can cause serious organ damage and death by triggering the secretion of pro-inflammatory cytokines such as TNF-alpha, IL-6 and IL-1 beta in bacterial infections.