Quicolor: A novel system for rapid antibacterial susceptibility testing

Kocagoz T., Ercis S., Darka O., Salmanzadeh-Ahrabi S., Kocagoz S., Hascelik G.

ANNALS OF MICROBIOLOGY, cilt.57, sa.1, ss.131-135, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/bf03175062
  • Dergi Adı: ANNALS OF MICROBIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.131-135
  • Anahtar Kelimeler: disk diffusion, susceptibility, rapid test, Quicolor, MICROSCAN WALKAWAY, FLUOROGENIC PANELS, IDENTIFICATION, VITEK, IMPACT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Early determination of antibacterial susceptibility increases the success of therapy, decreases unnecessary use of antibacterials and side effects and lowers the overall healthcare costs. We have evaluated a rapid antibacterial susceptibility test, Quicolor (Salubris Inc., Massachusetts, USA), which is based on a rapid culture medium that indicates growth early by changing its colour. Quicolor proved to be a reliable rapid test for determining antibacterial susceptibility, having an overall agreement of 97.6% with the conventional CLSI disk diffusion susceptibility test results. Between two methods overall agreement was 96.7% for Enterobacteriaceae, 96.8% for staphylococci and 94.2% for non-fermentative bacteria. There was only 0.6% major discrepancy in Enterobacteriaceae, 1.7% in staphylococci and 0.9% in non-fermentative bacteria. Since the test provides results in 3.5-6 h, it can provide the means to choose the right treatment regimen the same day the infectious agent is isolated.