Quicolor: A novel system for rapid antibacterial susceptibility testing


Kocagoz T. , Ercis S., Darka O., Salmanzadeh-Ahrabi S., Kocagoz S. , Hascelik G.

Annals of Microbiology, vol.57, no.1, pp.131-135, 2007 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1007/bf03175062
  • Title of Journal : Annals of Microbiology
  • Page Numbers: pp.131-135

Abstract

Early determination of antibacterial susceptibility increases the success of therapy, decreases unnecessary use of antibacterials and side effects and lowers the overall healthcare costs. We have evaluated a rapid antibacterial susceptibility test, Quicolor (Salubris Inc., Massachusetts, USA), which is based on a rapid culture medium that indicates growth early by changing its colour. Quicolor proved to be a reliable rapid test for determining antibacterial susceptibility, having an overall agreement of 97.6% with the conventional CLSI disk diffusion susceptibility test results. Between two methods overall agreement was 96.7% for Enterobacteriaceae, 96.8% for staphylococci and 94.2% for non-fermentative bacteria. There was only 0.6% major discrepancy in Enterobacteriaceae, 1.7% in staphylococci and 0.9% in non-fermentative bacteria. Since the test provides results in 3.5-6 h, it can provide the means to choose the right treatment regimen the same day the infectious agent is isolated.