Towards near-infrared photosensitisation: a photosensitising hydrophilic non-peripherally octasulfanyl-substituted Zn phthalocyanine

Tekdas D. A., Kumru U., Gurek A. G., Durmus M., Ahsen V., DUMOULIN F.

TETRAHEDRON LETTERS, cilt.53, sa.39, ss.5227-5230, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 39
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.tetlet.2012.07.062
  • Dergi Adı: TETRAHEDRON LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5227-5230
  • Anahtar Kelimeler: Zinc phthalocyanine, Near-infrared absorption, Fluorescence, Singlet oxygen generation, Photosensitiser, Photodynamic therapy
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

A Zn(II) phthalocyanine substituted with eight hydroxylated sulfanyl moieties in non-peripheral positions was designed to exhibit properties desired for photodynamic therapy: hydrophilicity, isomeric purity and near-infrared absorption in addition to high singlet oxygen generation. Photophysical and photochemical studies proved to be promising. (c) 2012 Elsevier Ltd. All rights reserved.