Towards near-infrared photosensitisation: a photosensitising hydrophilic non-peripherally octasulfanyl-substituted Zn phthalocyanine

Tekdas D. A., Kumru U., Gurek A. G., Durmus M., Ahsen V., DUMOULIN F.

TETRAHEDRON LETTERS, vol.53, no.39, pp.5227-5230, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 39
  • Publication Date: 2012
  • Doi Number: 10.1016/j.tetlet.2012.07.062
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.5227-5230
  • Keywords: Zinc phthalocyanine, Near-infrared absorption, Fluorescence, Singlet oxygen generation, Photosensitiser, Photodynamic therapy
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


A Zn(II) phthalocyanine substituted with eight hydroxylated sulfanyl moieties in non-peripheral positions was designed to exhibit properties desired for photodynamic therapy: hydrophilicity, isomeric purity and near-infrared absorption in addition to high singlet oxygen generation. Photophysical and photochemical studies proved to be promising. (c) 2012 Elsevier Ltd. All rights reserved.