Prepubertal Unilateral Gynecomastia: Report of 2 Cases

Demirbilek H., Bacak G., Baran R. T., Avci Y., Baran A., Keles A., ...Daha Fazla

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.6, sa.4, ss.250-253, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/jcrpe.1477
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.250-253
  • Anahtar Kelimeler: Gynecomastia, pubertal, prepubertal, unilateral, GIANT-CELL FIBROBLASTOMA, DOMINANT TRANSMISSION, EXCESS, BREAST
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Prepubertal unilateral gynecomastia is an extremely rare condition. At present, its etiology and management strategy are not well known. Two unrelated prepubertal boys of ages 8 and 9 who presented with complaints of unilateral enlargement of breast tissue are reported. Physical examination, biochemical, hormonal and oncologic work-up findings were normal. Both patients were treated with peripheral liposuction successfully. Histopathological and immunohistochemical examinations showed benign fibroglandular gynecomastia and intensive (3+) estrogen receptor expression in 100% of periductal epithelial cells. Although an extremely rare and generally benign condition, patients with prepubertal unilateral gynecomastia should have a full endocrine and oncologic work-up.