A Combined ULBP2 and SEMA5A Expression Signature as a Prognostic and Predictive Biomarker for Colon Cancer

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Demirkol S., Gomceli I., Isbilen M., Dayanc B. E., Tez M., Bostanci E. B., ...Daha Fazla

JOURNAL OF CANCER, cilt.8, sa.7, ss.1113-1122, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 7
  • Basım Tarihi: 2017
  • Doi Numarası: 10.7150/jca.17872
  • Dergi Adı: JOURNAL OF CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1113-1122
  • Anahtar Kelimeler: Colon Cancer, Prognosis, Biomarker, SOLUBLE UL16-BINDING PROTEIN-2, GROWTH-FACTOR RECEPTOR, GENE-EXPRESSION, SEMAPHORIN 5A, DRUG-SENSITIVITY, NKG2D RECEPTOR, TUMOR-CELLS, STAGE-II, RECURRENCE, IDENTIFICATION
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: Prognostic biomarkers for cancer have the power to change the course of disease if they add value beyond known prognostic factors, if they can help shape treatment protocols, and if they are reliable. The aim of this study was to identify such biomarkers for colon cancer and to understand the molecular mechanisms leading to prognostic stratifications based on these biomarkers.