Association of collagen I, IX and vitamin D receptor gene polymorphisms with radiological severity of intervertebral disc degeneration in Southern European Ancestor


Toktas Z. O. , Eksi M. Ş. , Yilmaz B., Demir M. K. , Ozgen S., KILIÇ T., et al.

EUROPEAN SPINE JOURNAL, cilt.24, ss.2432-2441, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 24 Konu: 11
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00586-015-4206-5
  • Dergi Adı: EUROPEAN SPINE JOURNAL
  • Sayfa Sayısı: ss.2432-2441

Özet

Several genomic loci have been previously found to be associated with intervertebral disc degeneration, so far. Data are mostly derived from northern European countries whereas data derived from Southern European Ancestor are limited. This study aimed to evaluate the association between radiological disease severity of lumbar disc degeneration and certain genetic loci in a sample of participants from Southern Europe.