Trends and factors associated with modification or discontinuation of the initial antiretroviral regimen during the first year of treatment in the Turkish HIV-TR Cohort, 2011-2017

KORTEN V., Gokengin D., Eren G., Yildirmak T., GENÇER S., Eraksoy H., ...More

AIDS RESEARCH AND THERAPY, vol.18, no.1, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1186/s12981-020-00328-6
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Keywords: Antiretroviral therapy, Treatment modification, Integrase strand transfer inhibitor, Treatment outcome, Cohort study, THERAPY, DURABILITY, INFECTION, EFFICACY, NAIVE
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Background: There is limited evidence on the modification or stopping of antiretroviral therapy (ART) regimens, including novel antiretroviral drugs. The aim of this study was to evaluate the discontinuation of first ART before and after the availability of better tolerated and less complex regimens by comparing the frequency, reasons and associations with patient characteristics.