Therapeutic Plasma Exchange in an Uncommon Disease: Stiff-Person Syndrome: Case Report


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Hergünsel O., Altun D. , Çukurova Z., Eren G., Yayla V.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.32, no.6, pp.1762-1765, 2012 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.5336/medsci.2011-24476
  • Title of Journal : TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Page Numbers: pp.1762-1765

Abstract

Stiff-Person syndrome (SPS) is a rare and disabling disorder characterized by continuous motor unit activity causing severe rigidity and episodic spasms in axial and limb muscles. It deteriorates the quality of life and causes a serious burden in the patient's life. It is frequently associated with other autoimmune diseases such as diabetes mellitus. Treatment with intravenous immunoglobulin, anti-anxiety drugs, muscle relaxants, anti-convulsants will improve symptoms, but will not cure the disorder. Therapeutic plasma exchange is an alternative treatment for the patients resistant to other treatment options. Here, we report a patient with SPS treated in intensive care unit and underwent therapeutic plasma exchange.