Cytotoxic effects of volatile anesthetics with free radicals undergoing laparoscopic surgery

Sivaci R., Kahraman A., Serteser M. , Sahin D., Dilek O.

CLINICAL BIOCHEMISTRY, vol.39, no.3, pp.293-298, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 2006
  • Doi Number: 10.1016/j.clinbiochem.2006.01.001
  • Title of Journal : CLINICAL BIOCHEMISTRY
  • Page Numbers: pp.293-298


Background: Free radicals induced by several diseases can trigger oxidative stress, leading to the production of malondialdehyde (MDA) and protein carbonyl content (CB). Volatile agents are able to increase the extent of oxidative status. However, the effects of these agents together with pneumoperitonium (Pp) have not been reported. We aimed to investigate the role of volatile anesthetics and ischemic injury during Pp oil free radicals and scavenging enzymes in laparoscopic abdominal surgery.