Efficacy, safety and prognostic features of resected colon carcinoma treated in "real world" practice: a retrospective cohort-study

Dane F., Ozturk M. A., Gumus M., Guven A., ALİUSTAOĞLU M., Cabuk D., ...More

JOURNAL OF BUON, vol.16, no.2, pp.257-264, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 2
  • Publication Date: 2011
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.257-264
  • Keywords: adjuvant treatment, colon cancer, fluorouracil, oxaliplatin, real world, POSTOPERATIVE ADJUVANT THERAPY, AMERICAN JOINT COMMITTEE, COLORECTAL-CANCER, STAGE-II, ELDERLY-PATIENTS, POOLED ANALYSIS, TUMOR-MARKERS, FLUOROURACIL, CHEMOTHERAPY, LEUCOVORIN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Purpose: Treatment outcomes and prognostic features of a specific cancer generally come from prospective randomized studies. It seems reasonable to ask the question whether the results of prospective randomized studies entirely reflect the results of the population treated in "real world" practice. Therefore we performed a retrospective cohort analysis in order to find out the efficacy of adjuvant chemotherapy as well as the prognostic factors of our patient population treated in daily practice, and compared these findings with those defined in the prospective studies.