Atıf İçin Kopyala
Canpolat F. E., Yurdakok M., Korkmaz A., Yigit S., Tekinalp G.
JOURNAL OF PEDIATRIC SURGERY, cilt.41, sa.6, ss.1134-1138, 2006 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
41
Sayı:
6
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Basım Tarihi:
2006
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Doi Numarası:
10.1016/j.jpedsurg.2006.02.003
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Dergi Adı:
JOURNAL OF PEDIATRIC SURGERY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.1134-1138
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Anahtar Kelimeler:
G-CSF, necrotizing enterocolitis, prematurity, GASTROINTESTINAL-TRACT, NITRIC-OXIDE, HUMAN FETUS, RAT MODEL, ERYTHROPOIETIN, INFANTS, RECEPTOR, PATHOGENESIS, CYTOKINES, WEIGHT
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Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli:
Hayır
Özet
Background/Purpose: The presence of granulocyte colony-stimulating factor (G-CSF) in human milk and the expression of G-CSF receptors on intestinal villous enterocytes of neonates suggest that G-CSF has a role in the development and integrity of the gastrointestinal tract. We hypothesized that enteral recombinant human G-CSF (rhG-CSF) given to preterm infants with necrotizing enterocolitis (NEC) in the earlier stages could protect against disease progression and complications.