Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report


Basaran R., Kaksi M., Onoz M., Balkuv E., Sav A.

CASE REPORTS IN NEUROLOGICAL MEDICINE, 2015 (ESCI İndekslerine Giren Dergi)

  • Basım Tarihi: 2015
  • Doi Numarası: 10.1155/2015/708472
  • Dergi Adı: CASE REPORTS IN NEUROLOGICAL MEDICINE

Özet

Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5-8%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences.