Features of incisura angularis biopsies in dyspeptic cases

Demir M., Neşe N., Saruç M. , Yüceyar H., Ayhan S.

Turkish Journal of Gastroenterology, vol.12, no.3, pp.211-213, 2001 (Journal Indexed in SCI Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 3
  • Publication Date: 2001
  • Title of Journal : Turkish Journal of Gastroenterology
  • Page Numbers: pp.211-213


Background/aims: In the Updated Sydney Classificati-on for gastritis the incisura angularis, where the metaplasia-dysplasia sequence is frequently observed, has been recommended as a fifth biopsy region in addition to four biopsies taken from gastric antrum and corpus. The aim of this study was to evaluate the necessity and value of this recommendation. Methods: The gastric biopsies of 150 cases with dyspeptic complaints were reexamined. According to the parameters of the Updated Sydney Classification, activity, mononuclear inflammatory infiltration, atrophy and intestinal metaplasia were evaluated on routine haematoxylin-eosin preparations. Toluidin blue was used to detect Helicobacter pylori. The presence of lymphoid follicles was also examined. Antrum+corpus findings and antrum+corpus+incisura angularis findings were compared using X2 test. Results: The only significant difference between the two groups was the presence of lymphoid follicles (p=0.036), while Helicobacter pylori (p=0.634), activity (p=0.12) atrophy (p=0.579) and intestinal metaplasia (p=0.56) were insignificant. Conclusion: It is considered that taking a fifth biopsy from the incisura angularis may be advantageous in detecting early stage MALT lymphoma.