THE ROLE OF CHITOTRIOSIDASE ACTIVITY AS A PROGNOSTIC BIOMARKER IN SARCOIDOSIS

Uysal P., Yurt S., Erman H., Korkmaz G. G., Yigitbas B. A., Kosar F., ...Daha Fazla

ACTA MEDICA MEDITERRANEA, cilt.31, sa.6, ss.1223-1228, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 6
  • Basım Tarihi: 2015
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1223-1228
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Introduction: Chitotriosidase (ChT) is a chitinase that is massively expressed by lipid-laden tissue macrophages in human beings. The aim of this study was to compare ChT activities in the serum and bronchoalveolar lavage (BAL) fluid and serum ChT levels with serum angiotensin converting enzyme (ACE) levels in patients with newly diagnosed pulmonary sarcoidosis (SARC), pulmonary tuberculosis (TB) and interstitial lung disease (ILD), all of which create difficulties in the differential diagnosis in daily practice.