Congenital glioblastoma multiforme - Case report and review of the literature

Seker A., Ozek M. M.

JOURNAL OF NEUROSURGERY, vol.105, no.6, pp.473-479, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 105 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.3171/ped.2006.105.6.473
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.473-479
  • Keywords: congenital glioblastoma multiforme, intratumoral hemorrhage, magnetic resonance imaging, pediatric neurosurgery, PRENATAL-DIAGNOSIS, FETAL GLIOBLASTOMA, BRAIN-TUMOR, MALIGNANT GLIOMAS, SONOGRAPHY, ASTROCYTOMA, CHILDHOOD, PROGNOSIS, FAILURE, P53
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Congenital intracranial tumors are rare. If such a lesion is detected before birth, it is usually an incidental finding on fetal ultrasonography. The definition of a "congenital" tumor is controversial. The authors report the case of a "definite" congenital glioblastoma multiforme (GBM) diagnosed with the aid of ultrasonography and fetal magnetic resonance (MR) imaging in the 37th week of gestation. Postnatal MR imaging revealed a massive tumor occupying the patient's left temporoparietooccipital area. Angiography was performed to assess vascularity and embolize the main feeding arteries. Surgery was performed, and the tumor was successfully excised completely.