Interleukin-1 beta and thiobarbituric acid reactive substance (TBARS) levels after phase I periodontal therapy in patients with chronic periodontitis

Tuter G., Kurtis B., Serdar M. A.

JOURNAL OF PERIODONTOLOGY, cilt.72, sa.7, ss.883-888, 2001 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 72 Konu: 7
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1902/jop.2001.72.7.883
  • Sayfa Sayıları: ss.883-888


Background: Interleukin-1 beta (IL-1 beta), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal tissue destruction. There is also a clearly defined and substantial role for free radicals or reactive oxygen species in periodontal destruction. The thiobarbituric acid reactive substances (TBARS) is a commonly applied test to measure free radical activity. The aims of this study were to investigate the amount of crevicular IL-1 beta, tissue TBARS levels, and the clinical status of patients with advanced chronic periodontitis and the effect of phase I periodontal therapy on these clinical parameters and measurements.