International Recommendations on Reirradiation by Intensity Modulated Radiation Therapy for Locally Recurrent Nasopharyngeal Carcinoma

Ng, Wai; Soong, Yoke; Ahn, Yong; AlHussain, Hussain; Choi, Horace; Corry, June; Gregoire, Vincent; Harrington, Kevin; Hu, Chao; Jensen, Kenneth; Kwong, Dora; Langendijk, Johannes; Le, Quynh; Lee, Nancy; Lin, Jin; Lu, Tai; Mendenhall, William; O'Sullivan, Brian; ÖZYAR, ENİS; Pan, Jian; Peters, Lester; Poh, Sharon; Rosenthal, David; Sanguineti, Giuseppe; Tao, Yungan; Wee, Joseph; Yom, Sue; Chua, Melvin; Lee, Anne

doi:10.1016/j.ijrobp.2021.01.041

International Recommendations on Reirradiation by Intensity Modulated Radiation Therapy for Locally Recurrent Nasopharyngeal Carcinoma

Ng W. T., Soong Y. L., Ahn Y. C., AlHussain H., Choi H. C. W., Corry J., ...Daha Fazla

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, cilt.110, sa.3, ss.682-695, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Derleme
Cilt numarası: 110 Sayı: 3
Basım Tarihi: 2021
Doi Numarası: 10.1016/j.ijrobp.2021.01.041
Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CINAHL, Compendex, EMBASE, Gender Studies Database, INSPEC, MEDLINE
Sayfa Sayıları: ss.682-695
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Purpose: Reirradiation for locally recurrent nasopharyngeal carcinoma (NPC) is challenging because prior radiation dose delivered in the first course is often close to the tolerance limit of surrounding normal structures. A delicate balance between achieving local salvage and minimizing treatment toxicities is needed. However, high-level evidence is lacking because available reports are mostly retrospective studies on small series of patients. Pragmatic consensus guidelines, based on an extensive literature search and the pooling of opinions by leading specialists, will provide a useful reference to assist decision-making for these difficult decisions.