Pharmacological assessment of Co<sub>3</sub>O<sub>4</sub>, CuO, NiO and ZnO nanoparticles via antibacterial, anti-biofilm and anti-quorum sensing activities

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Junejo B., ERYILMAZ M., RIZVANOĞLU S. S., PALABIYIK İ. M., Ghumro T., Mallah A., ...Daha Fazla

WATER SCIENCE AND TECHNOLOGY, cilt.87, sa.11, ss.2840-2851, 2023 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 87 Sayı: 11
  • Basım Tarihi: 2023
  • Doi Numarası: 10.2166/wst.2023.150
  • Dergi Adı: WATER SCIENCE AND TECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Analytical Abstracts, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chimica, Compendex, Environment Index, Geobase, Pollution Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.2840-2851
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

The resistance to many common antibiotics has dramatically increased disease-causing infections, especially those caused by pathogens. The creation of effective antimicrobial agents in the fight against infection has a new avenue of exploration thanks to nanotechnology. The combined effects of metal-based nanoparticles (NPs) are known to have intense antibacterial activities. However, a comprehensive analysis of some NPs regarding these activities is still unavailable. This study uses the aqueous chemical growth method to synthesize Co3O4, CuO, NiO and ZnO NPs. The prepared materials were characterized by scanning electron microscopy, transmission electron microscopy and X-ray diffraction techniques. The antibacterial activities of NPs were tested against Gram-positive and Gram-negative bacteria using the microdilution method, such as the minimum inhibitory concentration (MIC) method. The best MIC value among all the metal oxide NPs was 0.63 against Staphylococcus epidermidis ATCC12228 through ZnO NPs. The other metal oxide NPs also showed satisfactory MIC values against different test bacteria. In addition, the biofilm inhibition and antiquorum sensing activities of NPs were also examined. The present study presents a novel approach for the relative analysis of metal-based NPs in antimicrobial studies, demonstrating their potential for bacteria removal from water and wastewater.