The thyroid hormone profile was investigated in goitrous schoolchildren aged 6-11 years living in Antalya, an area with mild/moderate iodine deficiency. With few exceptions, the serum levels of T-4 and TSH were in the normal range in children with different grades of goiter. Compensatory elevated T-3 levels were detected in 24% of the subjects. Thyroid hormones did not differ significantly with respect to the urinary iodine (UI) level, No correlations were found between thyroid volume, UI excretion level and thyroid hormones. It was concluded that thyroid hormones, except compensatory T-3 elevation in some subjects, were not affected significantly in a mild/moderate iodine deficient area.