CORONARY ARTERY DISEASE, cilt.19, ss.513-519, 2008 (SCI İndekslerine Giren Dergi)
Background Experimental data demonstrated that inflammatory mediators, such as pro-inflammatory and anti-inflammatory cytokines and their receptors might have important role in the development and the progression of heart failure (HF). Statins were shown to downregulate inflammatory cytokines in HE Interleukin (IL)-10 is one of the most important anti-inflammatory cytokines. The effect of statin therapy on plasma IL-10 levels is not known in patients with HE We conducted this study to investigate the effects of fluvastatin therapy on plasma IL-10 cytokine concentration in patients with HE