The effect of serum levetiracetam concentrations on therapeutic response and IL1-beta concentration in patients with epilepsy


Gulcebi M. I. , Kendirli T., Turgan Z. A. , Patsalos P. N. , Onat F.

EPILEPSY RESEARCH, cilt.148, ss.17-22, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Objective: Assessment of the relevance between serum drug concentration to its therapeutic response is a valid monitoring strategy for the clinical efficacy of antiepileptic drugs (AEDs). Levetiracetam (LEV) is a broad spectrum AED with a possible anti-inflammatory effect. We aimed to determine the relationship between LEV concentrations and its therapeutic response, and the effect of LEV on IL1-beta concentrations in patients with epilepsy.