European Biological Variation Study (EuBIVAS): Within- and Between-Subject Biological Variation Data for 15 Frequently Measured Proteins


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Carobene A., Aarsand A. K., Guerra E., Bartlett W. A., Coskun A., Diaz-Garzon J., ...More

CLINICAL CHEMISTRY, vol.65, no.8, pp.1031-1041, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 65 Issue: 8
  • Publication Date: 2019
  • Doi Number: 10.1373/clinchem.2019.304618
  • Journal Name: CLINICAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1031-1041
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

BACKGROUND: The European Biological Variation Study (EuBIVAS) was established to deliver rigorously determined data for biological variation (BV). Here, EuBIVAS-based BV estimates are provided for alpha(1)-acid glycoprotein, alpha(1)-antitrypsin, albumin, beta(2)-microglobulin, ceruloplasmin, complement component 3, complement component 4, C-reactive protein (CRP), cystatin C, haptoglobin, IgA, IgG, IgM, soluble transferrin receptor (sTfR), and transferrin (Trf), together with their associated analytical performance specifications (APSs) and reference change values (RCVs).