The synthesis of an octasubstituted monohydroxylated phthalocyanine designed to investigate the effect of the presence of active moieties

Tarakci D. K. , Berber S., Zorlu Y., Atilla D., Ahsen V., DUMOULIN F.

NEW JOURNAL OF CHEMISTRY, vol.39, no.5, pp.3929-3935, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1039/c5nj00229j
  • Title of Journal : NEW JOURNAL OF CHEMISTRY
  • Page Numbers: pp.3929-3935


A monohydroxylated octasubstituted phthalocyanine, aimed at being used as a synthon for further conjugation, has been designed to offer rigorous comparison conditions to study the effect of the presence of an active moiety, compared to its non-functionalized symmetric analogs. After the validation of the concept using computational methods, the designed phthalocyanine was prepared and exhibited the expected suitable electronic absorption properties. Biotin conjugation was performed.