The synthesis of an octasubstituted monohydroxylated phthalocyanine designed to investigate the effect of the presence of active moieties

Tarakci D. K., Berber S., Zorlu Y., Atilla D., Ahsen V., DUMOULIN F.

NEW JOURNAL OF CHEMISTRY, vol.39, no.5, pp.3929-3935, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1039/c5nj00229j
  • Journal Name: NEW JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.3929-3935
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

A monohydroxylated octasubstituted phthalocyanine, aimed at being used as a synthon for further conjugation, has been designed to offer rigorous comparison conditions to study the effect of the presence of an active moiety, compared to its non-functionalized symmetric analogs. After the validation of the concept using computational methods, the designed phthalocyanine was prepared and exhibited the expected suitable electronic absorption properties. Biotin conjugation was performed.