The synthesis of an octasubstituted monohydroxylated phthalocyanine designed to investigate the effect of the presence of active moieties


Tarakci D. K. , Berber S., Zorlu Y., Atilla D., Ahsen V., DUMOULIN F.

NEW JOURNAL OF CHEMISTRY, cilt.39, ss.3929-3935, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 39 Konu: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1039/c5nj00229j
  • Dergi Adı: NEW JOURNAL OF CHEMISTRY
  • Sayfa Sayıları: ss.3929-3935

Özet

A monohydroxylated octasubstituted phthalocyanine, aimed at being used as a synthon for further conjugation, has been designed to offer rigorous comparison conditions to study the effect of the presence of an active moiety, compared to its non-functionalized symmetric analogs. After the validation of the concept using computational methods, the designed phthalocyanine was prepared and exhibited the expected suitable electronic absorption properties. Biotin conjugation was performed.