Electrophysiological Identification of Central Sensitization in Patients with Chronic Prostatitis

Korkmaz S., Karadag M. A. , Hamamcioglu K., Sofikerim M., Aksu M.

UROLOGY JOURNAL, vol.12, no.4, pp.2280-2284, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 2015
  • Journal Name: UROLOGY JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.2280-2284
  • Keywords: chronic pain, physiopathology, evoked potentials, somatosensory, neuropsychological tests, prostatitis, physiopathology, PELVIC PAIN SYNDROME, TREATMENT RESPONSE, MEN, FEATURES
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Purpose: Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a chronic pain condition and a common problem in urology clinics. Although many different etiologies and mechanisms exist, the exact cause of the disease has been unknown. Central sensitization (CS) is defined as an augmentation of responsiveness of central cortical neurons to input from peripheral nociceptive structures. Somatosensory evoked potentials (SEPs) is an electroneurophysiological method to assess cortical activity in somatosensory area of brain related to sensorial stimuli. We aimed to determine the presence of CS using the SEPs of dorsal penile nerve stimulation in patients with CP/CPPS.