Association between non-coding polymorphisms of HOPX gene and syncope in hypertrophic cardiomyopathy.


Gulec C., Abaci N., Bayrak F. , Bayrak E. K. , Kahveci G., Guven C., ...More

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, vol.14, no.7, pp.617-24, 2014 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 7
  • Publication Date: 2014
  • Doi Number: 10.5152/akd.2014.4972
  • Title of Journal : Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • Page Numbers: pp.617-24

Abstract

Objective: Homeodomain Only Protein X (HOPX) is an unusual homeodomain protein which regulates Serum Response Factor (SRF) dependent gene expression. Due to the regulatory role of HOPX on SRF activity and the regulatory role of SRF on cardiac hypertrophy, we aimed to investigate the relationship between HOPX gene variations and hypertrophic cardiomyopathy (HCM).