Association between non-coding polymorphisms of HOPX gene and syncope in hypertrophic cardiomyopathy


Gulec C., Abaci N., Bayrak F., Bayrak E. K. , Kahveci G., Guven C., et al.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.14, ss.617-624, 2014 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 14 Konu: 7
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/akd.2014.4972
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Sayfa Sayısı: ss.617-624

Özet

Objective: Homeodomain Only Protein X (HOPX) is an unusual homeodomain protein which regulates Serum Response Factor (SRF) dependent gene expression. Due to the regulatory role of HOPX on SRF activity and the regulatory role of SRF on cardiac hypertrophy, we aimed to investigate the relationship between HOPX gene variations and hypertrophic cardiomyopathy (HCM).