Kaposi's sarcoma: The efficacy of a single fraction of 800 cGy

Yildiz F., Ozyar E., Uzal D., Sahin S., Atahan I.

DERMATOLOGY, vol.195, no.2, pp.142-144, 1997 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 195 Issue: 2
  • Publication Date: 1997
  • Doi Number: 10.1159/000245717
  • Journal Name: DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.142-144
  • Keywords: Kaposi's sarcoma, radiotherapy, THERAPY, RADIOTHERAPY
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background: Although Kaposi's sat-coma is the most common neoplasm in association with AIDS, classic Kaposi's sarcoma is rare. The best treatment modality is still unclear. Methods: Between December 1993 and December 1995, 42 fields in 12 patients with Kaposi's sarcoma were treated at our department, Only 3 patients had a history of renal transplantation and immunosuppressive treatment, A single dose of 800 cGy with 4-6 MeV electron beams was delivered to all patients. Results: Complete response rates at the 1st, 6th and 12th months after treatment were 45.2, 62 and 89.7%. respectively. Side effects included various degrees of hyperpigmentation and mild edema and fibrosis in patient. Conclusion: Our results suggest that a single application of 800 cGy is as effective as a more protracted course of radiotherapy with a comparable complication rate.