Effect of fish oil, olive oil, and vitamin E on liver pathology, cell proliferation, and antioxidant defense system in rats subjected to partial hepatectomy

Kirimlioglu V., Kirimlioglu H. , Yilmaz S., Ozgor D., Coban S., Karadag N., ...More

TRANSPLANTATION PROCEEDINGS, vol.38, no.2, pp.564-567, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1016/j.transproceed.2006.02.005
  • Page Numbers: pp.564-567


The high capacity of liver regeneration after partial hepatectomy (PH) is well known. This study investigated the role of the antioxidant defense system in regeneration among Wistar-albino male rats subjected to 70% partial hepatectomy after a pretreatment period of 2 weeks with eicosapentanoic acid (EPA) rich fish oil (FO), first pressed virgin olive oil (00), or vitamin E. The control group of 10 rats underwent PH only. On postoperative day 3, all rats were humanely killed.