Hodgkin Lymphoma In Childhood And Adolescence: A Single-Institution Experience


Yücel S., Güral Z., Bozkurt M., İribaş Çelik A., Kebudi R., Ağaoğlu F.

Journal of Community Medicine And Public Health Reports. , cilt.4, sa.6, ss.1-6, 2023 (Hakemli Dergi)

Özet

Objective: Historical assessment of HL treatment shows a successful model of combining therapies and achieving excellent outcomes. Centers with reporting epidemiologic knowledge, treatment schedules, and survival rates will make progress regarding their prognostic factors. So, we aimed to report treatment schedules and survival rates of pediatric Hodgkin lymphoma patients treated 20 years ago.

Methods and Materials: A single-center, retrospective study was performed on patients with pediatric Hodgkin lymphoma who underwent chemotherapy, radiotherapy, or both between 1988 and 2002. The demographic and clinical characteristics of the patients were recorded. Survival rates, including disease-free and overall, were calculated.

Results: There were 96 patients with a median age of 10 years. All stage I-II and IIIA patients who received combined or alone ChT and RT were in complete remission at the end of the RT, except one patient who did not receive RT was disease-free at the time of analysis. 5 and 10 years, disease-free survival rates were 95 % and 95 %. Also, for 5 and 10 years, overall survival rates were 99 % and 95 %.

Conclusion: HL has had higher survival rates with particularly effective treatment modalities over the years. So, in this study, pediatric HL patients also had been observed with high response rates and prolonged survival.