Imbalance between cysteine proteases and inhibitors in a baboon model of bronchopulmonary dysplasia


Altiok O., Yasumatsu R., Bingol-Karakoc G. , Riese R., Stahlman M., Dwyer W., ...Daha Fazla

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, cilt.173, sa.3, ss.318-326, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 173 Konu: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1164/rccm.200503-425oc
  • Dergi Adı: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
  • Sayfa Sayıları: ss.318-326

Özet

Rationale: Bronchopulmonary dysplasia (BPD) continues to be a major morbidity in preterm infants. The lung pathology in BIRD is characterized by impaired alveolar and capillary development. An imbalance between proteases and protease inhibitors in association with changes in lung elastic fibers has been implicated in the pathogenesis of BIRD.