Backgrounds: The aim of this study is to compare the results of single-site laparoendoscopic donor nephrectomy with open extraction (LESSDN-OE) and vaginal extraction (LESSDN-VE).
Methods/Materials: We analysed the data of 18 female donors who underwent LESSDN-OE (Group I:9) and LESSDN-VE (Group II:9) in our center. All donors had one renal arter and vein. Parameters regarding donor age, body mass index (BMI), length of hospitalization, duration of surgical procedure, amount of blood loss, warm and cold ischemia times, side of graft nephrectomy, averages for postoperative (PO) visual analogue pain scores at 0th and 1th days (VAS-0, VAS-1), peri-and PO complications of donors, averages of PO fever at 1h and 2th days, averages of PO arterial oxygen saturation at 0h and 1th days, graft function at discharge and PO sixth month were compared between two groups statistically with Mann-Whitney U test.
Results: All of the donors in both groups had left sided nephrectomy except two in Group I. No significant difference in terms of donor age, BMI, mean operative time, amount of blood loss, length of hospitalization, warm ischemia time, VAS-0, PO fever and oxygen saturation was observed between two groups. However, cold ischemia time was lower in Group I (Z=3.13, p<0.01) and VAS-1 was lower in Group I (Z=1.98, p<0.05). No perioperative complications occured for donors and recipients in both groups. In both groups, two donors presented with fever higher than 38 degrees of centigrade due to PO atelectasia at first PO day. An acute rejection episode which was treated successfully occured for two recipients of Group II in first six mount after transplantation. Graft function at discharge and graft survival at PO sixth month were similar in both groups.
Conclusion: Since our first priority is to minimize the morbidity of donors, LESSDN-VE can be chosen in selected female donors not only for better cosmetic outcomes but also similar graft survival rate as seen in LESSDN-OE.