Chlamydial Infections and Their Laboratory Diagnoses


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Yıldırım A., Soyoğul Gürer Ü., Çevikbaş A., Onganer E.

Erciyes Tıp Dergisi, vol.20, no.4, pp.287-292, 1998 (National Refreed University Journal)

  • Publication Type: Article / Review
  • Volume: 20 Issue: 4
  • Publication Date: 1998
  • Title of Journal : Erciyes Tıp Dergisi
  • Page Numbers: pp.287-292

Abstract

Chlamydia trachomatis (C. trachoma/is) infections are the most common bacterial cause of sexually transmitted diseases in the world. in women, these infections often result in such serious reproductive tract complications as pelvic inflammatory disease, infertility, and ectopic pregnancy, and an infected woman can pass the infection on to her newborn during delivery. The pervasiveness of this often asymptomatic disease necessitates that health care providers actively look C. trachoma/is infection, especially in young women. C. trachoma/is is an obligate intracellular organism therefore tissue culture is the best diagnostic procedure. Antigen detection, the enzyme immunoassay test and nucleic acid hybridization tests remain important challenges. Nucleic acid amplification technologies make non-invasive urine testing cost effective and easily performed in primary care. Historically the diagnosis of C. trachoma/is infections has been difficult, but newer chlamydia diagnostic tests have become clinically available in the past decade.