Assessment of p21, p53 expression, and Ki-67 proliferative activities in the gastric mucosa of children with Helicobacter pylori gastritis

Saf C., Gulcan E. M., ÖZKAN F., Saf S. P. C., Vitrinel A.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.27, sa.2, ss.155-161, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/meg.0000000000000246
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.155-161
  • Anahtar Kelimeler: gastric atrophy, gastritis, Helicobacter pylori, intestinal metaplasia, Ki-67, p21, p53, INTESTINAL METAPLASIA, PRECANCEROUS PROCESS, INFECTION, POPULATION, CARCINOMA, CLASSIFICATION, EPIDEMIOLOGY, PREVALENCE, CANCERS, SAMPLE
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background Helicobacter pylori that is generally acquired in childhood and infects the gastric mucosa is considered to be responsible for many pathobiological changes that are linked to the pathogenesis of gastric cancer. Although the majority of studies on the subject have been carried out in adults, there are a limited number of studies on children that reflect the early period of infection and may be of greater significance.