Effect of Corticosteroid Dose and Duration of Administration on Colonic Anastomosis

Baca B., ÖZBEN V., Boler D. E., Onur E., Hamzaoglu İ. H., Karahasanoglu T., ...More

INFLAMMATORY BOWEL DISEASES, vol.16, no.12, pp.2162-2167, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 12
  • Publication Date: 2010
  • Doi Number: 10.1002/ibd.21331
  • Journal Name: INFLAMMATORY BOWEL DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2162-2167
  • Keywords: Corticosteroid dose, duration of methylprednisolone treatment, anastomose healing, inflammatory bowel disease, POUCH-ANAL ANASTOMOSIS, INTESTINAL ANASTOMOSES, ULCERATIVE-COLITIS, COLLAGEN-SYNTHESIS, CROHNS-DISEASE, RESTORATIVE PROCTOCOLECTOMY, DIVERTING-ILEOSTOMY, BURSTING STRENGTH, BOWEL, RATS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background: Surgical intervention under concomitant steroid therapy can be complicated by impaired anastomotic healing. The aim of this experimental study was to investigate the effects of a corticosteroid (methylprednisolone) on healing colonic anastomoses in relation to the dose and duration of administration.