Akademik Veri Yönetim Sistemi
TURKISH JOURNAL OF PATHOLOGY, cilt.21, sa.1-2, ss.27-30, 2005 (ESCI)
Plexiform fibrohistiocytic tumor (PFHT) is a rare soft tissue neoplasm with low grade nature. Histologically it is characterized by a plexiform proliferation of mononuclear histiocyte-like cells, multinucleated osteoclast-like giant cells and spindle fibroblast-like cells in variable proportions. We report a case of a 26-year old woman with a PFHT on the forehead region. The patient had noticed solitary, hard painless nodule with 7 mm diameter at her forehead region two months ago. The lesion was excised in another center and the material was diagnosed as fibroma. The lesion was recurred two weeks later and a second operation was carried out. Immunohistochemistry for CD68, CD34 smooth mucle actin were peroformed in Department of Pathology, Cerraphasa Medical Faculty. CD68 was positive in many of mononuclear macrophages and smooth muscle actin was positive in spindle fibroblast-like cells. The tumor cells was negative for CD34 and the findings were found to be consistent with the diagnosis of PFHT. Our case was worth to discuss because PFHT is a new entity and head and neck region is an unusual localization as compared to extremity .