Role of GDF-15 as an inflammatory marker in patients with psoriasis vulgaris


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Tasolar M. K. , ERFAN G. , Raimoglu O., Albayrak H., Yanik M. E.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, vol.55, no.4, pp.184-188, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.4274/turkderm.galenos.2021.73444
  • Title of Journal : TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Page Numbers: pp.184-188
  • Keywords: Psoriasis vulgaris, PASI, GDF-15, C-REACTIVE PROTEIN, TNF-ALPHA LEVELS, SERUM-LEVELS, CARDIOVASCULAR RISK, IL-22, DIFFERENTIATION, CYTOKINES, EXPRESSION, SEVERITY, IL-17

Abstract

Background and Design: Psoriasis is a chronic, inflammatory disease, and several biochemical markers play role in its inflammatory process. This study measured the levels of interleukin-12 (IL-12), IL-17a, IL-22 and IL-23, high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-alpha) and serum growth differentiation factor-15 (GDF-15) and aimed to detect the relationship of serum GDF-15 level with inflammation and disease severity.