INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.28, sa.1, ss.521-524, 2015 (SCI İndekslerine Giren Dergi)
Background: The etiopathogenesis of Hashimoto's thyroiditis (HT) - has not been clearly elucidated although the role of chronic inflammation, endothelial dysfunction, and imbalance between pro- and anti-inflammatory cytokines has been established. Transforming growth factor beta 1 (TGF beta 1) is required to maintain immune homeostasis, and is implicated in lymphocyte infiltration, production of autoantibodies and thyrocyte destruction seen in patients with HT.