THE EFFECTS OF 30 HZ, 50 HZ AND 100 HZ CONTINUOUS THETA BURST STIMULATION VIA TRANSCRANIAL MAGNETIC STIMULATION ON THE ELECTROPHYSIOLOGICAL PARAMETERS IN HEALTHY INDIVIDUALS

Ozdemir Z., ACAR E., Soysal A.

IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE, vol.74, pp.41-49, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 74
  • Publication Date: 2021
  • Doi Number: 10.18071/isz.74.0041
  • Journal Name: IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.41-49
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background and purpose - Transcranial magnetic stimulation is a non-invasive procedure that uses robust magnetic fields to create an electrical current in the cerebral cortex. Dual stimulation consists of administering subthreshold conditioning stimulation (CS), then suprathreshold test stimulation (TS). When the interstimulus interval (ISI) is 1-6 msec, the motor evoked potential (MEP) decreases in amplitude; this decrease is termed "short interval intracortical inhibition" (SICI); when the 151 is 7-30 msec, an increase in MEP amplitude occurs, termed "short interval intracortical facilitation" (SICF). Continuous theta burst stimulation (cTBS), often applied at a frequency of 50 Hz, has been shown to decrease cortical excitability. The primary objective is to determine which duration of cTBS achieves better inhibition or excitation. The secondary objective is to compare 50 Hz cTBS to 30 Hz and 100 Hz cTBS.