NUCLEAR MEDICINE COMMUNICATIONS, cilt.14, sa.6, ss.471-478, 1993 (SCI-Expanded)
Thirty patients were prospectively studied to assess the value of radionuclide ventriculography (RNV) during step-wise dobutamine infusion for the detection of coronary artery disease (CAD). Radionuclide ventriculography was performed under basal conditions and during dobutamine infusion at each 10 mug kg-1 min-1 dose increment from 10 to a maximum of 40 mug kg-1 min-1. The test response was considered positive if the ejection fraction (EF) decreased by more than 5% or if segmental contraction abnormalities developed. Dobutamine stress testing was well tolerated, no complications and no significant arrhythmia were observed.