Evaluation of c-kit (CD 117) expression as a prognostic factor in testicular germ cell tumors: an Izmir Oncology Group (IZOG) study


Salman T., Yildiz E., Yildiz İ. , Yayuzer D., Unlu M., Varol U., ...More

JOURNAL OF BUON, vol.20, no.4, pp.1054-1060, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2015
  • Title of Journal : JOURNAL OF BUON
  • Page Numbers: pp.1054-1060

Abstract

Purpose: Despite the successful use of targeted and molecular therapies in other cancers, little progress has been made in the management of testicular germ cell tumors (TGCTs). c-kit (CD 117) is a good target for cancer treatment and possesses an impressive role in the current oncological practice. We aimed to evaluate c-kit expression in early stage TGCTs as a prognostic factor.