PHARMACOKINETICS OF INTRAMUSCULAR ADMINISTERED BETA-CAROTENE AND ITS EFFECTS ON REPRODUCTION IN SHEEP


OZPINAR H., OZPINAR A. , BILAL T., TURKALP I., FIRAT A.

WIENER TIERARZTLICHE MONATSSCHRIFT, vol.82, no.8, pp.229-231, 1995 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 8
  • Publication Date: 1995
  • Title of Journal : WIENER TIERARZTLICHE MONATSSCHRIFT
  • Page Numbers: pp.229-231

Abstract

In the first experiment, blood levels of p-carotene were determined after i.m. administration of 7.4, 14.9, 22.3, 27.9 and 37.2 mu mol beta-carotene/kg BW3/4 (metabolic body weight), once a month in foursheep of the same breed and age. Blood samples were drawn 1 day after each injection and continued in two day intervals for 21 days. The lowest dose, leading to a detectable serum concentration, was 14.9 mu mol beta-carotene/kg BW3/4. AS th, higher dosages were given, higher blood levels were determined and the p-carotene remained longer in the circulation. In lactating sheep P-carotene was also found in milk.