Syringocystadenocarcinoma Papilliferum With Squamous Cell Carcinoma Differentiation and With Locoregional Metastasis

ARSLAN H., Diyarbakirh M., BATUR Ş., Demirkesen C.

JOURNAL OF CRANIOFACIAL SURGERY, vol.24, no.1, 2013 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1097/scs.0b013e31826cffc6
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: SCACP, SCACP with regional lymph node metastasis, SCACP with squamous cell carcinoma, OF-THE-LITERATURE
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Syringocystadenocarcinoma papilliferum is the rare malignant counterpart of a more common, benign adnexal neoplasm known as syringocystadenoma papilliferum. Review of the literature identified 21 cases of syringocystadenocarcinoma papilliferum. Most reported SCACP seem to represent examples of in situ adenocarcinoma or invasive adenocarcinomas, whereas to our knowledge, only 3 cases were described as SCACP with squamous cell carcinoma. In the present series of 2 cases, we report of SCACP with squamous differentiation and 1 case of SCACP with regional lymph node metastasis. The risk of regional lymph node metastasis is low with SCACP, but it should be kept in mind for the risk of regional metastasis of its morphological type of invasive squamous cell carcinoma.