Components of ambient air pollution affect thrombin generation in healthy humans: the RAPTES project


Strak M., Hoek G., Steenhof M., Kilinc E. , Godri K. J. , Gosens I., et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, cilt.70, ss.332-340, 2013 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 70 Konu: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1136/oemed-2012-100992
  • Dergi Adı: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
  • Sayfa Sayısı: ss.332-340

Özet

Objectives Increases in ambient particulate matter (PM) have been associated with an elevated risk of stroke, myocardial ischaemia and coronary heart disease, with activation of blood coagulation likely playing an important role. PM-mediated activation of two major activation pathways of coagulation provides a potential mechanism for the observed association between PM and cardiovascular disease. However, it remains unclear which specific characteristics and components of air pollution are responsible.