Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices


Giuntini F., DUMOULIN F. , Daly R., Ahsen V., Scanlan E. M. , Lavado A. S. P. , ...More

NANOSCALE, vol.4, no.6, pp.2034-2045, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1039/c2nr11947a
  • Title of Journal : NANOSCALE
  • Page Numbers: pp.2034-2045

Abstract

Polyacrylamide nanoparticles bearing two orthogonal reactive functionalities were prepared by reverse microemulsion polymerisation. Water-soluble photosensitisers and peptide or carbohydrate moieties were sequentially attached to the new nanospecies by orthogonal conjugations based on copper-catalysed azide-alkyne cycloaddition and isothiocyanate chemistry.