Investigation of Px1 Gene Expression, Serum Gpx1 and Selenium Levels on Colorectal Cancer

Iplik E. S., NALKIRAN İ., Turan S., Arikan S., YAYLIM İ., ERGEN H. A.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.9, sa.1, ss.65-70, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/clinexphealthsci.2018.1239
  • Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.65-70
  • Anahtar Kelimeler: Colorectal cancer, glutathione peroxidase 1, selenium, OXYGEN SPECIES ROS, GLUTATHIONE-PEROXIDASE, NUTRITIONAL PREVENTION, MESSENGER-RNA, APOPTOSIS, RISK, SUPPLEMENTATION, BINDING, CELLS, TRIAL
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objective: Colorectal cancer is one of the first lines when examined the death cause of cancer. It is well known that family history, and racial and ethnic background and daily life are related with colorectal cancer and its treatment options are surgery, chemotherapeutic agents, and radiotherapy. One of the factors that play a critical role in the development of colorectal cancer is the oxidative stress. In this research, we aimed to investigate the association of level of glutathione peroxidase 1 (GPX1) and selenium element with colon cancer.